The role of pro-inflammatory cytokines (IL-6 and IL-8) and anti-inflammatory cytokines (IL-10) in COPD patients with differences in soluble IL-6 and IL-8 levels being higher in COPD patients than in non-COPD patients, while Lower IL-10 in COPD patients than in non-COPD patients; each of which found a statistically significant difference (P < 0.01). Here, CXCL8 is linked to chronic obstructive pulmonary disease.