In contrast, only type II IFN (IFN-γ) was upregulated in the SLE patients (IFN-γ, HC vs. SLE, P < 0.01), and only type I IFNs (IFN-α2 and IFN-β1) were upregulated in AIBD (IFN-α2, HC vs. AIBD, P < 0.05, IFN-β1, HC vs. AIBD, P < 0.05). The gene discussed is IFNA2; the disease is systemic lupus erythematosus.