For example, there are many reasons for insomnia patients with fever, such as influenza57, tuberculosis58, pneumonia59, tumors60, and neurological disorders61, which would be involved in various molecular pathways, including the immune system pathway (e.g., intestinal immune network for IgA production and intestinal immune network for IgA production), signal transduction pathway (e.g., cAMP signaling pathway and AMPK signaling pathway), and infectious disease pathway (e.g., Influenza A and Tuberculosis) (Fig. 6). This evidence concerns the gene CD79A and insomnia.