The model of dataset 3 included the peptide SFPLSSEHAK (Cadherin-2) combined with ICARS score, presence or absence of cerebellar dysarthria, disease stage, CSF NfL, orthostatic hypotension score, UPDRS right leg agility score, Hoehn and Yahr score, UPDRS postural stability score, and verbal fluency score. The gene discussed is NEFL; the disease is orthostatic hypotension.