An interesting study published by Maier et al. using single-cell RNA sequencing in a murine model of lung adenocarcinoma lesions recently identified a DC population with high levels of maturation markers such as CD80, CD86 and MHC II, and also immunoregulatory genes Pdcd1lg2 (PD-L2 gene) and Cd200. This evidence concerns the gene CD80 and lung adenocarcinoma.