CPN1 and infection: Following model optimization, the neuroprotective effects of histone deacetylase inhibitors trichostatin A (TSA) and givinostat, a DNA methyltransferase inhibitor RG108, and rifampin, an antibiotic used to treat this infection that has previously been shown to have neuroprotective effects [44–46], were investigated in this model and in the presence of Cpn, LPS and Aβ.