All of them were men: one patient developed an air leak on the 2nd postoperative day, four were diagnosed with heart failure (BNP > 15.000), one was excluded due to a breach of the study protocol (violation of the time of CDR), and one developed pneumonia, bronchopleural fistula (BPF), and pleural empyema. The gene discussed is NPPB; the disease is pleural empyema.