The MIRA antigen stimulation assays used to generate the IMMUNEcode 2.0 database (Nolan et al., 2020) identified sets of TCR β-chains associated with recognition of a SARS-CoV-2 antigen using CD8+ T cells enriched from PBMC samples from 62 COVID-19 diagnosed patients and 26 COVID-19-negative subjects. This evidence concerns the gene CD8A and COVID-19.