The 10 genes with the highest interconnection levels were maintained, including CDK1, CCNA2, CCNB2, KIF11, BUB1B, NCAPG, CCNB1, DLGAP5, MAD2L1, and ASPM, suggesting their pivotal role in the regulation of tumor development by SKA1/2/3 genes (Figure 6(d)). Here, BUB1B is linked to neoplasm.