The analysis of the ROC curve and the Youden index revealed that the optimal cutoff values of LDH levels and the GGT/ALT ratio to predict the recurrence of HCC after surgery were 80.5 U/l (AUC = 0.647, P = 0.002) and 3.1338 (AUC = 0.744, P = 0.001), respectively (Figure 1 and Table 2). The gene discussed is GPT; the disease is hepatocellular carcinoma.