Serum ratio of GGT/ALT was significantly associated with AFP levels (<400 vs. ≥400 ng/ml) (P ≤ 0.001), largest tumor size (<50 vs. ≥50 mm) (P = 0.001), Edmondson grade (I-II vs. III-IV) (P = 0.028), microvascular invasion status (P = 0.001), and the Milan (P = 0.002) and Hangzhou criteria (P = 0.018) (Table 3). The gene discussed is AFP; the disease is neoplasm.