We performed six classification tasks, including (i) tumor vs. normal, (ii) lobular vs. ductal carcinoma histological type, (iii) estrogen receptor (ER) status (positive or negative), (iv) progesterone receptor (PR) status (positive or negative), (v) HER2 receptor status (positive or negative), (vi) PAM50 four-way status (Luminal A, Luminal B, Basal, or HER2 enriched), and (vii) TP53 Mutation status. This evidence concerns the gene ESR1 and neoplasm.