DISC1 and psychiatric disorder: Dual-hit GE mice mimicking both the genetic [mutation of the intracellular hub of developmental processes disrupted-in-schizophrenia 1 (DISC1) gene; Brandon and Sawa, 2011] and the environmental [challenge by maternal immune activation (MIA)] background that has been related to mental illness, have abnormal patterns of early electrical activity both in PFC and HP (Hartung et al., 2016; Xu et al., 2019, 2021; Chini et al., 2020).