Single PCa- and NOR-TMA spots could be categorized with respect to numbers of TET1-expressing cells as “TET1-high” (presence of numerous TET1-expressing cell clusters) (Fig. 1C.1), “TET1-moderate” (presence of a few scattered TET1-expressing cells) (Fig. 1C.2), or “TET1-negative” (absence of TET1-expressing cells) (Fig. 1C.3). Here, TET1 is linked to posterior cortical atrophy.