Further differential methylation analyses of 30 TET1 CpG probes in PCa versus NOR revealed 18 significantly hypermethylated CpG probes in PCa (4 in the promoter, 12 in the 5′-UTR, and 2 in the gene body) and 4 significantly hypomethylated CpG sites in PCa (one in the 5′-UTR and 3 in the gene body) (Fig. 2A.1, Additional file 2: Table S3 and Additional file 1: Fig. S3). Here, TET1 is linked to posterior cortical atrophy.