IFNL1 and infection: Among the proteins differentially expressed in the COVID-19 infection samples almost all are up-regulated during the infection, including many proteins related to cytokine response, for example interferon lambda 1 (IFNL1) and the chemotactic factors C-X-C motif chemokine ligand 10 (CXCL10) and C-C motif chemokine ligand 8 (CCL8), which is known to play a role in neoplasia and inflammatory host responses (Fig. 3e).