PGLYRP1 and fungal infectious disease: However, there was a significant effect of fungal infection on pathogen recognition receptors PGRP-LC (p < 0.0013), PGRP-S1 (p < 0.0001), and transcription factors REL1 (Toll Pathway) (p < 0.0001) and REL2 (Imd pathway) (p < 0.0001) in the mosquito Ae.