A total of 10 metabolic-related proteins were elevated including peroxiredoxin-6, neutral alpha-glucosidase AB, 3-ketoacyl-CoA thiolase (3-KAT), hydroxyacyl-CoA dehydrogenase alpha (HADHA), transaldolase, cytosolic nonspecific dipeptidase, lactate dehydrogenase A and B, dihydrolipoyl dehydrogenase and nucleoside diphosphate kinase B. Several of these metabolic proteins have previously been investigated in AML. This evidence concerns the gene HADHB and acute myeloid leukemia.