Using microarrays and a high-throughput qPCR approach, Valleron et al. screened for certain snoRNA patterns specific to AML and ALL patients when compared to CD34+ progenitors, CD33+ myeloid cells (for AML patients), CD3+ and CD19+ lymphoid cells (for ALL patients) as well as healthy donors. The gene discussed is CD33; the disease is acute myeloid leukemia.