Finally, in a Brd2 (+/−) haploinsufficient mouse model of juvenile monoclonal epilepsy (JME), the number of GABAergic neurons is reduced in the striatum and primary motor cortex, suggesting that Brd2-dependent neurogenesis is critical for the proper differentiation of specific neuronal cell types [38]. This evidence concerns the gene BRD2 and juvenile myoclonic epilepsy.