The results show that again, GGpp triggered incorporation of wild-type UBIAD1 into vesicles (Figure 2C, lanes 2 and 14), whereas the efficiency of GGpp-induced vesicle incorporation was reduced for all 20 SCD-associated variants of the prenyltransferease (lanes 3–12; 15–24). The gene discussed is UBIAD1; the disease is Schnyder corneal dystrophy.