The expression levels of CD28, CD59, LAG3, TCRab and TIGIT were higher, while CD45, CD45RO, RORγ, OX40 and Tbet lower in cluster 16 in acute pneumonia, stable pneumonia, acute asthma and stable asthma (Figures 4B and 7B). The gene discussed is TBX21; the disease is susceptibility to pneumonia measurement.