GRAMD4 and hepatocellular carcinoma: Subsequently, we used Kaplan–Meier survival analysis to explore the effects of GRAMD4 on the OS of HCC patients, and the results revealed that HCC patients with relatively lower GRAMD4 expression had shorter OS in both the Tongji and TCGA cohorts (Figure 1F and H), as well as shorter DFS in the Tongji cohort (Figure 1G).