TP53 and colorectal carcinoma: Therefore, to examine the CHEK1‐targeting effects in CRC cells in terms of P53 status, we carried out an in‐depth analysis using AZD7762 in a panel of P53 cell lines composed of the P53 mutant HT29 cell line, P53 WT HCT116 cell line and P53 KO HCT116 cell line (Supplementary Figure S5K).