Exportin-1 was identified as an abundant protein in EVs released by prostate cancer cells (Duijvesz et al. 2013), and we observed increased exportin-1 protein in EVs derived from CD47− T cells as compared to EVs from WT cells using western blot analysis of the 20–40% density gradient fraction but not in the 40–60% gradient fraction (Figure S3E). Here, XPO1 is linked to Familial prostate cancer.