Systemic suppression of CD47 expression enhances tumor ablation when combined with ionizing radiation, adoptive T cell transfer, chemotherapy, or a CTLA4 checkpoint inhibitor (Maxhimer et al. 2009; Soto-Pantoja et al. 2014; Feliz-Mosquea et al. 2018; Schwartz et al. 2019). The gene discussed is CD47; the disease is neoplasm.