CCDC6 and embryonal carcinoma: In human NTERA-2 embryonal carcinoma cells, the CCDC6 depletion, upon a transient shCCDC6 transfection, prevented the cells death following exposure to hydrogen peroxide, in comparison to the control CCDC6 proficient cells (shCTRL) in which we observed a decrease of nearly 50% of the cells viability, limited by the apoptosis inhibitor Z-VAD-fmk (Fig. 4 A, left).