SOCS3 and pancreatic neoplasm: Reid-Lombardo et al. found that in patients with resection of pancreatic cancer, the SOCS3 rs8064821 C>A polymorphism was associated with a survival advantage of approximately 10 months compared with noncarriers Reid-Lombardo et al. [27], while Jiang et al. analyzed the association between the genetic polymorphism of the SOCS3 gene and the incidence and progression of hepatocellular carcinoma (HCC) Jiang et al. [28].