Additionally, mutations in CHEK2 and BRCA2 have been linked to CLL and MDS [4,8,9], RAD51 in acute myeloid leukemia (AML) and MDS [10,11], MLH1 in MDS [12,13], and BRCA1 in AML [4]. The gene discussed is CHEK2; the disease is acute myeloid leukemia.