No significant association was observed between KC patients and healthy controls concerning FOXP3 rs3761548 genotypes (P = 0.98), the allele frequency distribution was also nonsignificant (P = 0.9; OR = 1.03; 95%CI [0.63–1.68]), with minor T allele frequency 0.35 and major G allele frequency 0.65. The gene discussed is FOXP3; the disease is keratoconus.