In other studies, eugenol induced apoptosis in skin tumors via the c-Myc pathway, H-ras from the ras oncogene gene family, and by regulating p53 gene expression [13], as well as inhibiting the growth and induction of apoptosis through the p53 gene and associated pathways in colorectal [12] and cervical cancer cells [15]. Here, TP53 is linked to skin neoplasm.