NLRP3 and type 2 diabetes mellitus: Thus, the study of this particular inflammasome (NLRP3) and its components (CASP-1 and IL-18) was chosen as a focus point of our research, considering the promising results of its assessment as a potential biomarker for the periodontal clinical status [2] and its upregulation in periodontal patients with uncontrolled type 2 diabetes [6, 8, 11].