Based on the mentioned data, the authors postulated that the role of FABP4 in vitiligo pathogenesis could be mediated not only through its metabolic function (demonstrated hyperglycemia and dyslipidemia) but also via its immune-mediated mechanisms including up-regulated inflammatory cytokines,27 over-expressed auto-reactive tissue-resident memory T-cells32 and stimulated endothelial cells.34 The gene discussed is FABP4; the disease is vitiligo.