Western blot assay showed that circVAPA knockdown-induced suppressive effect on the expression of Ki-67 and promoting effect on the expression of Bax were both largely reversed by the silence of miR-342-3p (Fig. 5G), suggesting that circVAPA knockdown suppressed the proliferation and induced the apoptosis of NSCLC cells largely by upregulating miR-342-3p. This evidence concerns the gene BAX and non-small cell lung carcinoma.