In addition, the expressions of p-AMPK and p-mTOR in each group were analyzed by immunohistochemistry and Western blot method, and the correlation between p-AMPK as well as p-mTOR protein expression and diameter dilation was analyzed by Pearson correlation analysis, which aimed at constructing VS-1 nanoparticles successfully and identifying its influence in the formation of AAA. This evidence concerns the gene MTOR and triple-A syndrome.