In FCD type II, mammalian target of rapamycin (mTOR) pathway mutations of genes within this pathway, including AKT1, AKT3, DEPDC5, MTOR, NPRL2/3, PIK3CA, PIK3R2, and TSC1/2 mutations, can be found [10–12]. This evidence concerns the gene MTOR and isolated focal cortical dysplasia type II.