MORC2 could activate the Wnt/β-catenin signaling pathway and stimulate the recruitment of tumor-associated macrophages, contributing to the promotion of lung tumor growth and metastasis in a series of lung cancer cell lines, including A549, PC-9, H1299, NCI-H2170, NCI-H226, and LL/2 cells [70]. This evidence concerns the gene MORC2 and lung carcinoma.