PSMD12 was involved in “DNA damage_ATM/ATR regulation of G2/M checkpoint: nuclear signaling”, “Cell cycle_Initiation of mitosis”, “Cell cycle_ESR1 regulation of G1/S transition”, “Cell cycle_Nucleocytoplasmic transport of CDK/cyclins”, and “Mitogenic action of estradiol/ESR1 (nuclear) in breast cancer” (Figure 14 and Supplementary Table 7). The gene discussed is ATR; the disease is breast carcinoma.