Evaluation for CHI included an 18F-DOPA PET/CT scan on day 13 showed diffuse labeling of the pancreas, Fig. 2B. A next generation sequencing (NGS) panel for 11 genes in CHI including ABCC8, KCNJ11, GCK, GLUD1, HADH, HNF1A, HNF4A, INS, INSR, SLC16A1, and UCP2 and a whole exome sequencing panel with > 2000 genes for diseases in childhood were all normal. Here, GCK is linked to congenital isolated hyperinsulinism.