For instance, the 15-LOX transcript was expressed in all types of colon and lung cancer cell lines while among 7 types of breast cancer cell lines (MB231, H2380, SKBR3, T47D, ZR75, MCF-WT, and MCF7-adr), only SKBR3 cells were not able to express 15-LOX also the expression of 15-LOX was not detectable in PC-3 (prostate cancer cells). The gene discussed is ALOX15; the disease is Familial prostate cancer.