HIF1A and non-small cell lung carcinoma: Thus, the present study explored the impacts of circ_0016760 depletion on NSCLC malignant development and tube formation under hypoxia, and determined whether the inner mechanism responsible for the effects of circ_0016760 on PESV-mediated NSCLC malignant progression involved circ_0016760/miR-29b/HIF1A axis.