First, we found that the levels of CDK1, CDC20, PLK1, KIF11, NDC80, AURKB, MAD2L1, BUB1B, CCNB1, and CCNB2 in sarcoma tissues were upregulated compared to those in control tissues by GEPIA (http://gepia.cancer-pku.cn/). The gene discussed is MAD2L1; the disease is sarcoma.