Indeed, DNA methylation levels at the ABCA1 promoter region in EAT were 1.8-fold higher in patients with CAD compared with the NCAD group [21.92 (10.29–36.93) % vs 10.81 (7.12–18.74) %, p = 0.003; Fig. 1A]. Here, ABCA1 is linked to coronary artery disorder.