Anxiety-related GABA receptors affect serotonin and norepinephrine, antagonists of neurotransmitter systems such as corticotropin-releasing factor and substance P, minimize glutamate neurotransmission, such as metabolic glutamate receptors, and promote neurotrophic factors that tend to increase neurogenesis (Gilhotra and Dhingra, 2010). The gene discussed is CRH; the disease is Anxiety.