Finally, we detected the expression of RACK1 protein in melanocytes from different sources (MC, MCV-N, MCV-L, PI3V) and found that in the melanocytes derived from vitiligo (whether it is around the skin lesion, the normal part of the patient, or immortalized cells) the expressions of RACK1 protein were significantly lower than that of normal melanocytes (P<0.05, Figure 4A). This evidence concerns the gene RACK1 and vitiligo.