TLR4 and atherosclerosis: Cluster of differentiation 36 (CD36) is anothercell surface receptor of macrophages that identifies theendogenous ligands produced during atherosclerosis.It may facilitates the TLR4 signaling pathway wheninteracts with endogenous ligands such as TMAO (39).Wang and his colleagues showed that TMAO increasesthe expression of CD36 in murine macrophages (2).