Tumor-specific mutations often occur in subunits exclusive to one of the three major mSWI/SNF sub-complexes, canonical BAF (cBAF), Polybromo-associated BAF (PBAF), or non-canonical BAF (ncBAF, alternatively GBAF), suggesting that these specialized complexes have distinct roles in epigenetic mechanisms of tumor suppression in specific cancers16. Here, BANF1 is linked to neoplasm.