Compared to LRRK2 PD patients, GBA PD patients showed greater annual changes in the baseline SBR range over 0.9 (LMM; interaction between baseline SBRs and group; estimate = −0.0652, SE = 0.0297, nominal p = 0.030; Fig. 4c and Supplementary Table 1), however, the difference became no more significant after correction for multiple testing. This evidence concerns the gene LRRK2 and Parkinson disease.