CD4 and glioblastoma: In parallel, our multiplex immunofluorescent staining also showed a concordant increase in the number of CD4+ and CD8+ T cells per mm2 of tumor section in GBM.pembro patients compared to GBM.rec patients (Fig. 1i, j), while the number of CD14+ myelo-monocytic cells was similar (Supp Fig. 1g).