Analysis of immunohistochemistry on serial tumor sections showed significant inverse correlations between LMP1 and p-PERK (R = −0.361; P = 4 × 10−4) (Fig. 6c) and between E7 and p-PERK (R = −0.281; P = 3 × 10−7) (Fig. 6g) in these NPC and cervical carcinoma tissue samples, respectively. The gene discussed is EIF2AK3; the disease is nasopharyngeal carcinoma.