In TCGA-BLCA cohort, the most common gene fusions included 10 FGFR3-TACC3 fusions, 9 ITGB6-LOC100505984 fusions, 5 AFF1-PTPN13 fusions, 4 PPARG-SYN2 fusions, 4 GPR110-TNFRSF21 fusions, and 4 TSEN2-PPARG fusions (Fig. S16D). Here, TACC3 is linked to bladder transitional cell carcinoma.