IL22 and asthma: In our study, we have administrated mice directly with the recombinant murine IL-22 in OVA-induced asthma model mice to investigate the role of IL-22, finding that allergic airway inflammation was significantly attenuated by IL-22 administration, including a decreased number of eosinophils in BALF, reduced inflammatory cell infiltration around the bronchi and their accompanying vessels and decreased AHR.