The three clusters generated contained genes or proteins involved in apoptosis (BIRC3, BIRC5, PARP1, CASP8, and CASP9), transcriptional dysregulation in cancer (CDKN1B, RELA, CDKN1A, MYC, JUN, and MMP9), and cancer progression (CCND1, CASP3, CTNNB1, WNT1, and VEGFA) pathways. The gene discussed is CDKN1B; the disease is cancer.