CASP8 and cancer: The 16 CBs (BIRC3, BIRC5, CASP3, CASP8, CASP9, CCND1, CDKN1A, CDKN1B, CTNNB1, JUN, MMP9, MYC, PARP1, RELA, VEGFA, and WNT1) short-listed in this study formed three prominent clusters that were part of the apoptotic, transcriptional misregulation, or cancer progression pathways (Figure 6).