The three clusters generated contained genes or proteins involved in apoptosis (BIRC3, BIRC5, PARP1, CASP8, and CASP9), transcriptional dysregulation in cancer (CDKN1B, RELA, CDKN1A, MYC, JUN, and MMP9), and cancer progression (CCND1, CASP3, CTNNB1, WNT1, and VEGFA) pathways. Here, CASP8 is linked to cancer.